Which factors may increase the chance of a psoriasis outbreak?

The correct answer highlights the significance of infection and smoking in relation to psoriasis outbreaks. Psoriasis is an autoimmune condition that can be triggered by various environmental and lifestyle factors. Infections, particularly streptococcal throat infections, have been identified as potential triggers for psoriasis flare-ups, particularly in individuals who are genetically predisposed. Additionally, smoking is known to exacerbate the condition, as it can impact the immune system and promote inflammation.

While genetic predisposition is indeed a significant factor, it primarily indicates an individual's likelihood to develop psoriasis rather than directly causing outbreaks. High humidity can influence skin conditions in various ways, but it is generally not associated with an increase in psoriasis flare-ups. Excessive sun exposure can be a double-edged sword; while some patients find that moderate sun exposure can improve their symptoms, too much sun can lead to skin damage and trigger flares in some individuals. Therefore, the combination of infection and smoking is specifically linked to increasing the likelihood of experiencing a psoriasis outbreak.