Which demographic is most commonly affected by Madelung deformity?

Madelung deformity is a skeletal condition that predominantly affects the wrist and forearm, characterized by abnormal growth of the radius and subsequent changes in the carpal bones. This condition is most commonly observed in females, particularly during adolescence. The reason this demographic is most affected is that the deformity often manifests during periods of rapid growth, which typically occurs during puberty—a stage more notably pronounced in females compared to their male counterparts.

This condition is associated with genetic factors and might be linked to dysplasia of the growth plate in the radius, making adolescent girls the primary demographic observed in clinical cases. Understanding the specific demographic affected by Madelung deformity helps in early diagnosis and effective management, particularly since many patients might experience functional impairment or pain in wrist use if not addressed appropriately.