What is the primary symptom associated with hyperthyroidism?

In the context of hyperthyroidism, all of the mentioned symptoms—goiter, weight loss, and increased appetite—are interconnected and often manifest as a result of the condition. Hyperthyroidism is characterized by an overproduction of thyroid hormones, which accelerates the body's metabolism.

A goiter, which is an enlargement of the thyroid gland, can occur as the gland attempts to produce more hormones, often in response to an autoimmune process, such as Grave's disease. Weight loss is another hallmark symptom, as the accelerated metabolism leads to the body burning calories more rapidly than normal, even when food intake increases. Additionally, individuals with hyperthyroidism often experience an increased appetite due to the heightened metabolic rate, resulting in a desire to consume more food to compensate for energy expenditure.

Thus, the primary symptom associated with hyperthyroidism encompasses a combination of these features, which makes the choice of "All of the above" accurate and comprehensive in reflecting the diverse manifestations of hyperthyroidism.