The presence of which sign suggests a possible acute liver disease?

The presence of dark urine is indicative of acute liver disease due to the liver's role in processing bilirubin, a byproduct of red blood cell breakdown. When the liver is damaged or diseased, it may not effectively process bilirubin, leading to an accumulation of this substance in the bloodstream. This excess bilirubin can then be excreted through the kidneys, resulting in urine that appears darker than usual.

In the context of acute liver disease, other symptoms might include jaundice, pale stools, and possible abdominal pain, but dark urine is a particularly telling sign. This symptom reflects the liver's impaired ability to conjugate bilirubin and may suggest conditions such as hepatitis or liver failure. Understanding this connection helps in recognizing potential liver issues early, allowing for prompt medical intervention.